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Sayansi yosavuta yotchuka: mvetsetsa chiyani hydrogel mu mphindi imodzi? Amagwiritsidwa ntchito yanji?

[Sayansi Tanthauzo]

Ma Hydrogels ndi maukonde amtundu wa ma polima a hydrophilic, otchedwa ma colloidal gels, momwe madzi amafalikira. Mapulogalamu atatu amtunduwu amachokera ku maunyolo a hydrophilic polima omwe amathandizidwa molumikizana. Chifukwa cholumikiza pamtanda, mawonekedwe amtundu wa hydrogel sangasungunuke ndimadzi ambiri (doi: 10.1021 / acs.jchemed.6b00389). Ma Hydrogels nawonso amalowerera kwambiri (amatha kukhala ndi madzi opitilira 90%) maukadaulo achilengedwe kapena opangira ma polima. Mawu oti "hydrogel" adapezeka koyamba m'mabuku mu 1894 (doi: 10.1007 / BF01830147). Poyamba, kafukufuku wama hydrogel amayang'ana pa makina ocheperako olumikizana ndi ma polymer kuti aphunzire mawonekedwe ake, monga kutupa / kutupa kinetics ndi kufanana, kusungunuka kosiyanasiyana, kusintha kwa voliyumu gawo ndikutsutsana, ndikufufuza ntchito zotere. Monga ophthalmology ndikuperekera mankhwala. Ndikupitilira kopitilira muyeso kwa kafukufuku wa hydrogel, cholinga chake chasintha kuchokera pamaukonde osavuta kupita kumanetiwe "oyankha". Pakadali pano, ma hydrogel osiyanasiyana omwe amatha kuyankha kusintha kwachilengedwe monga pH, kutentha, ndi magetsi ndi maginito apangidwa. Hydrogel actuator yomwe imayankha magetsi ndi maginito ikufunsidwa. Komabe, ma hydrogel panthawiyo nthawi zambiri anali ofewa kwambiri kapena osalimba kwambiri, zomwe zimalepheretsa kugwiritsa ntchito kwambiri. Pakubwera kwa Zakachikwi zatsopano, ma hydrogel adalowanso m'nyengo yatsopano, ndikuwongolera kwazinthu zawo. Kuchita bwino kumeneku kwadzetsa maphunziro ambiri osiyana siyana a ma hydrogel. Masiku ano, njira zosiyanasiyana zamagetsi zokhala ndi zida zowononga mphamvu zitha kugwiritsidwa ntchito kupanga ma hydrogel omwe ali olimba kuposa minofu ndi mafupa. Kuphatikiza apo, imakwanitsanso ntchito zina, monga kudzichiritsa, mayankho olimbikitsira angapo, kulumikiza, kunyowa kwambiri, ndi zina. Kupanga kwatsopano kwa hydrogel yolimba kwakulitsa kwambiri kugwiritsa ntchito kwa zinthuzi m'malo osiyanasiyana, kuphatikiza maloboti ofewa, yokumba ziwalo, mankhwala obwezeretsanso, ndi zina zambiri (doi: /10.1021/acs.macromol.0c00238).

Cholinga chachikulu】

1. Scaffold mu zomangamanga (doi: 10.1002 / advs.201801664).

2. Pogwiritsidwa ntchito ngati scaffold, hydrogel ikhoza kukhala ndi maselo aumunthu okonzekera minofu. Amatsanzira 3D microenvelo yama cell (doi: 10.1039 / C4RA12215).

3. Gwiritsani zitsime zokutidwa ndi hydrogel pazikhalidwe zama cell (doi: 10.1126 / science.1116995).

4. Ma hydrogel omwe ali ndi vuto lachilengedwe (amatchedwanso "ma gels anzeru" kapena "ma gels anzeru"). Ma hydrogel amenewa amatha kuzindikira kusintha kwa pH, kutentha kapena kusungunuka kwa metabolite ndikutulutsa zosinthazi (doi: 10.1016 / j.jconrel.2015.09.011).

5. Hydrogel ya jakisoni, yomwe ingagwiritsidwe ntchito ngati chonyamulira mankhwala pochizira matenda kapena chonyamulira cell kuti zisinthe kapena zomangamanga (doi: 10.1021 / acs.biomac.9b00769).

6.Kulimbikitsidwa kotulutsidwa kwa mankhwala osokoneza bongo. Mphamvu ya Ionic, pH ndi kutentha zitha kugwiritsidwa ntchito ngati zoyambitsa kuwongolera kumasulidwa kwa mankhwala (doi: 10.1016 / j.cocis.2010.05.016).

7. Perekani mayamwidwe amitsempha ya necrotic ndi fibrotic, degreasing and debridement

8. Ma Hydrogel omwe amatenga ma molekyulu ena (monga glucose kapena ma antigen) amatha kugwiritsidwa ntchito ngati biosensors kapena DDS (doi: 10.1021 / cr500116a).

9. Matewera otayika amatha kuyamwa mkodzo kapena kuyika zopukutira zaukhondo (doi: 10.1016 / j.eurpolymj.2014.11.024).

10. Magalasi olumikizirana (silicone hydrogel, polyacrylamide, silicon-munali hydrogel).

11. Ma electrode azachipatala a EEG ndi ECG ogwiritsa ntchito ma hydrogel opangidwa ndi ma polima olumikizana ndi mtanda (polyethylene oxide, polyAMPS ndi polyvinylpyrrolidone).

12. Mabomba a Hydrogel.

13. Makonzedwe apadera ndi matenda.

14. Kuyika madontho ochuluka.

15. Zodzala m'mawere (zowonjezera m'mawere).

16. Guluu.

17. Tinthu tating'onoting'ono tomwe timagwiritsa ntchito kusunga chinyontho m'nthaka m'malo ouma.

18. Zovala kuti muchiritse zakupsa kapena zilonda zina zovuta. Mabala a gelisi amathandiza kwambiri popanga kapena kusunga malo opanda madzi.

19. Kusungira mankhwala kwa ntchito zakunja; makamaka mankhwala a ionic omwe amaperekedwa ndi iontophoresis.

20. Chida chomwe chimafanana ndi minyewa ya nyama, yomwe imagwiritsidwa ntchito poyesa kumamatira kwa mucosal kwamachitidwe operekera mankhwala (doi: 10.1039 / C5CC02428E).

21. Kutentha kwamagetsi. Mukaphatikizidwa ndi ayoni, imatha kutulutsa kutentha kuchokera pazida zamagetsi ndi mabatire, ndikusintha kosinthira kutentha kukhala magetsi.

Kupita kwathu pakadali pano】

Pakadali pano, mapulogalamu athu a hydrogel amagwiritsidwa ntchito kwambiri mu cosmetology ndi chithandizo chamankhwala, ndikukhalabe otsogola pamakampani a hydrogel kunyumba ndi akunja pankhani yaukadaulo, ndipo QA \ QC imakhala yolimba.

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Nthawi yamakalata: Aug-11-2021